Bravelle™ (urofollitropin) — For Intramuscular or Subcutaneous Injection

What is Bravelle?

Bravelle™ is a follicle stimulating hormone (FSH), one of the hormones that stimulates the ovary to make mature eggs. Bravelle is used to stimulate the development of multiple follicles in women undergoing assisted reproductive technology treatments (ART).


How Do I Use Bravelle?

Here are step-by-step instructions for taking Bravelle™ (urofollitropin):



Flip plastic caps off of 1 vial of diluent and as many vials of powder as you have been instructed to use
Clean the rubber stoppers of all vials with alcohol
Using a 3cc syringe with a 1 ½” needlePull the plunger back to the 1cc mark

Carefully remove the needle from the syringe.


Twist the Q-Cap™ onto the syringe.


Insert the Q-Cap™ through the rubber stopper of the vial of diluent


Invert the vial.

Push on the plunger injecting 1cc of air into the vial of diluent (to break the vacuum)
Withdraw 1cc of diluent by letting go and then pulling back on the plunger
Remove the needle from the vial

Inject 1cc of diluent into the first vial of powder if it does not dissolve instantly, (swirl don’t shake) the contents


Invert the vial, withdraw all the liquid

If you are using more than 1 vial of powder inject this mixture into the 2nd vial of powder
Continue injecting the mixture into vials of powder until you dissolve all your recommended powders

Remove the vial from the Q-Cap™ at an angle and pull off.


Twist off the Q-Cap™


If you are injecting subcutaneously replace it with a ½” needle


Gently push on plunger until air pocket is gone and expel a drop of liquid

How to give a subcutaneous injection

There are three places that a subcutaneous injection may be given: the abdomen, the thigh, or the back of your arm as shown here

Select your injection site (the abdomen is preferred)

Cleanse the area with alcohol and let dry. Do not blow on it.

Take a pinch of the fatty tissue you have cleansed. The injection is given here.

Hold the syringe like a pencil or a dart approximately 1 inch away from the skin.

Insert the needle quickly (not hard), with one fluid motion, into the skin.

Let go of the pinch of skin. Depress the plunger and inject all of the medication. Pull the needle straight out.

Apply pressure to the injection site with a sterile gauze pad.

Never reuse needles or syringes.

Dispose of the syringe in a biohazard container such as a Sharps container – or in a sealable, unbreakable plastic container such as a laundry detergent bottle.

Please be aware that some of these instructions may vary based on your particular situation or preference.