Progesterone (for Intramuscular Injection)

What is Progesterone? 


Progesterone, one of the reproductive hormones, is needed to increase the receptivity of your endometrium for implantation of an embryo and is used as part of an assisted reproductive technology (ART).


How Do I Use Progesterone?

Here are step-by-step instructions for administering an intramuscular progesterone injection:

Wash your hands thoroughly and make sure the surface you work on is clean.

Use an alcohol swab to cleanse the rubber stoppers of the progesterone medication.

Using the 3cc syringe with a 1½ inch needle, pull back on the plunger to the 1cc mark.

Pierce the rubber stopper of the progesterone vial. Inject 1cc of air into the vial.

Turn the vial upside down, making sure the tip of the needle is below the fluid level. Withdraw the dosage ordered. Progesterone is an oil. It will pull into the syringe more slowly than sterile water does as when you use your other fertility medications.

Pull out the needle and replace the cap. Pull back on the plunger to clear the needle of any medication. Remove the needle from the syringe and replace with a new 1½ inch needle. 

With the needle pointing toward the ceiling, flick the side of the syringe to disperse the air bubbles and the air pocket at the top of the syringe, then gently push the plunger to eliminate any air until you expel one or two drops of liquid from the tip of the needle.

Gently push on plunger until air pocket is gone and expel a drop of liquid

How to give an intramuscular injection


This is an injection that you give into a muscle.

Here are step-by-step instructions for administering an intramuscular injection.

Lying down-or standing with your weight off of the side to be injected-locate the upper outer quadrant (or quarter) of your buttock. The injection is given here. 

Take a deep pinch between your thumb and forefinger and wipe with alcohol. Then let dry. 

Place the needle into this pinch of tissue and muscle completely, leaving none of the needle exposed.

Draw back on the plunger. If you are accidentally in a blood vessel, blood will appear in the syringe. If so, pull the needle out, replace it with a new, sterile needle, and repeat the process.

Slowly push the plunger all the way to inject the medication, and pull the needle straight out. 

Alternate between your left and right sides, each time you give yourself an injection. 

Apply pressure and massage the injection site gently for thirty seconds after you administer the shot.

Never reuse needles or syringes.

Dispose of the syringe in a biohazard container such as a Sharps container or in an unbreakable plastic container such as a laundry detergent bottle that you can seal. 

Please be aware that some of these instructions may vary based on your particular situation or preference.